COENZYME Q10: Benefits, Side Effects, Uses, Dosage, Warnings?
Coenzyme Q10 provides various health benefits. We'll see if CoQ10 (ubiquinone) can also help lose weight, and under what conditions.
Coenzyme Q10 (CoQ10 or ubiquinone also called) is a fat-soluble compound found in every cell of your body (especially in mitochondria). CoQ10 is critical in the production of energy within each cell in the human body. Ubiquinone is essential for healthy cells, body tissues and organs . It is manufactured in the body and also provided by the power . Coenzyme Q10 acts as a member of another class of substances : enzymes. The role of enzymes is to facilitate and act as a catalyst (favorisateur element even essential to a chemical or biochemical reaction while standing out unchanged) for countless chemical reactions in the human body. Coenzymes as COQ10 as activities enzymes .
Ubiquinone has powerful antioxidant effects, and destroys free radicals in your body . Because we can synthesize this coenzyme in our body, the Q10 is not considered a vitamin (although some people call it Vitamin Q). For this coenzyme is synthesized in the body, an adequate intake of vitamin B6 is required. Role of Q10 in energy production is of particular importance to athletes and bodybuilders. coenzyme This helps produce energy in the form ATP (adenosine triphosphate, the only usable by human muscle power) in the body. ATP is responsible for several processes such as protein production and muscle contraction. CoQ10 works with vitamin E since it plays a critical role in maintaining our reserves of vitamin E and their antioxidant capacity. Ubiquinone also has a unique ability to increase the use of oxygen in our bodies.
What is the Coenzyme Q10?
An enzyme has two parts:
Part One : a protein,
Part two : either a vitamin or a mineral.
When this second part is a vitamin, the enzyme is called a coenzyme. Coenzyme Q 10 has a similar structure to vitamin K, and it acts as a catalyst in many chemical reactions that lead to the production of energy, namely ATP. Your body stores enough to support between ATP 5 and 8 minutes of vigorous physical activity . And ATP must be constantly produced. For this energy production occurs, your body needs good ubiquinone reserves. 's heart and liver contain the highest ubiquinone levels in the body. Coenzyme Q10 greatly helps maintain a healthy heart elsewhere. Various studies have found that as one ages, the reserves of CoQ10 in our body decreases (up to -72% in the core at a certain age). Young people and healthy produce about 300 mg of coenzyme Q10 daily, but levels begin to decline from 30 years.
Ubiquinone has various health benefits. Coenzyme Q10 is not only an antioxidant , it can also help fight against a number of diseases like diabetes, gingivitis, heart failure, etc. Here are some health benefits Q10: 1) To help lose weight Coenzyme Q10 may help weight loss because it helps to stimulate the body's metabolism . However, it is not a miracle supplement to absolutely take to lose weight. In fact, CoQ10 supplementation may be beneficial only if you are actually suffering from a deficiency of coenzyme Q10 in your body. The good news is that if you really suffer from a lack of co-enzyme Q10 in your body, then take a CoQ10 supplement will help you lose two times more weight compared to individuals who do not have a deficiency (according to an American study).
However, remember that taking Q10 supplements for weight loss (only if you suffer from a deficiency before taking ubiquinone) must be in support of a healthy and balanced diet and a fitness training program. 2) ubiquinone is an essential substance in cell respiration, electron transfer, ATP production, and control of oxidation reactions. 3) To assist the heart to function better CoQ10 plays a key role in the treatment of cardiovascular disease (including heart failure, and certain types of cardiomyopathy). An American study, 641 people with congestive heart failure were divided into groups randomly to receive either CoQ10 (2 mg per kg body weight) or placebo in addition to standard treatment (in 2 cases).
People who took CoQ10 had a significant reduction in the severity of symptoms and hospitalizations. 4) Assist the treatment of cancer and Parkinson's disease A study published in 1961 had found that people with cancer also had very low levels of CoQ10 in the blood. Other studies have found that ubiquinone helps strengthen the immune system and could be used as a secondary treatment of cancer. An American study from 2009, published in the journal "Archives of Neurology," found positive links between the effects high doses of ubiquinone on Parkinson's disease. 80 people with early Parkinson's disease took either varying doses of CoQ10 or placebo four times daily for 16 months. The study found that all participants who taken coenzyme Q10 are doing better than the participants who took the placebo.
The results were remarkable in the group that took the larger dose of Q10 (ubiquinone 1200 mg per day) since the progression of Parkinson's disease was slowed by 44% in this group compared to the placebo group. Participants placed in the groups taking 300 and 600 mg of CoQ10 had a slowdown of 20% of Parkinson's disease compared to placebo. 5) Various other studies have found that taking supplements of Q10 helps to fight against the angina and reduce hypertension . 6) Fight against gingivitis A small study examined the topical application of CoQ10 to the periodontal pocket. 10 periodontitis patients over 30 periodontal pockets were selected for the study .
During the first three weeks, patients applied CoQ10. They then observed a significant improvement in symptoms. 7) Contribute to fight diabetes In a 12-week study, 74 people with type 2 diabetes were randomized to receive (for 12 weeks so) or CoQ10 100 mg twice daily, or 200 mg of fenofibrate (a lipid regulating drug) per day, or both, or neither. Researchers found that ubiquinone supplementation significantly improved blood pressure and glycemic control . However, two other studies have shown that CoQ10 supplementation has no effect on glycemic control. Studies with a larger number of people are needed to confirm the hypothesis. 8) Protect the skin (in theory) Q10 is recognized as capable of helping the immune system, increasing the body's energy, and more to act as an antioxidant . And since owning a healthy immune system helps maintain healthy skin, and that antioxidants help the body fight free radicals and aging of the skin, increase the rate of Q10 in the body by taking a supplement CoQ10 (including cosmetics such as skin conditioners for faces) could theoretically be good for the skin ( this coenzyme is indeed a small molecule that can penetrate quite easily in the cells of the skin ). However, the efficacy not systematically result in practical benefits. And no large study has yet been able to demonstrate the potential benefits of Q10 in the skin. You should know that CoQ10, like vitamin C, can be disabled by the oxygen present in the air.
Various studies have found that taking high doses of coenzyme Q10 may cause some people nausea, vomiting, dizziness, headaches, more frequent stomach problems, loss of appetite, feelings discomfort in the throat or upper chest, heartburn . Some people may develop allergic reactions to Q10 as rash, hives, itching , unexplained swelling, wheezing or difficulty breathing or swallowing. Other studies have also reported minor side effects when taking large doses of CoQ10. However, these side effects can be avoided by taking smaller doses (no more than 100 mg) several times a day instead of a single high dose. ubiquinone Safety has not been established in women pregnant or nursing and children .
Dose CoQ10 Supplements
Taking supplements of coenzyme Q 10 is expected to remain between 30 and 90 mg per day. Higher doses may be prescribed by a doctor in the context of serious diseases. RegimesMaigrir.com recommends that you consult a doctor before considering taking any nutritional supplement. clinical effect Q10 supplements is not immediate and may take up to 8 weeks to be felt. Ubiquinone is fat-soluble (soluble in fats) so it is better to absorb for meals that contain oil or grease. Find out at the same time if the hormone DHEA may contribute to weight loss .
What is our average consumption of coenzyme Q10 food?
A Danish study in 2009 found that the average intake of CoQ10 through food is between 3 and 5 mg, and most people do not consume more than 10 mg per day in their diet. Larger sources coenzyme Q10 are food: meat, organs of animals, poultry, fish oil, trout, soybean oil, nuts, broccoli, wheat germ, spinach, peanuts. Vitamin B6 is very important for coenzyme Q10 is synthesized in the body . Foods rich in vitamin B6 are: potatoes baked with skin, bananas, chickpeas, chicken breasts, pork chops, roast beef, fish, tomatoes, avocados and sunflower seeds. Supplementation ubiquinone is often motivated by the fact that the amount of CoQ10 present in natural foods is much reduced in their cooking .
Interactions with other drugs
Ubiquinone can reduce the body's response to anticoagulant drugs such as warfarin (Coumadin). If you are taking an anticoagulant (or another drug), talk to your doctor before taking the Q10. based drugs statins (such as Lipitor, Mevacor and Pravachol) to reduce cholesterol may hinder Coenzyme Q10 production in the body. For this reason, many doctors ask patients to take supplements of Q10. Beta blockers are used to reduce high blood pressure also lowered the amount of CoQ10 in the body and produce a variety of side effects. Ubiquinone can reduce these side effects dramatically. CoQ10 may also reduce insulin requirements in people with diabetes.
Did you know?
The CoQ10 was discovered in 1957 by Dr. Frederick Crane (University of Wisconsin, USA). Since then, more than 5,000 studies on the coenzyme have been published. Many were made in Japan, where ubiquinone is still very popular. What do you think of the Q10? Do you take supplements of coenzyme Q10? Have you ever tried to lose weight with CoQ10? Read comments or add your opinion below on this page. If you liked this article, thank you for recommending it on Facebook, to tweet, to give it a +1 on Google Plus vote.
As coenzyme Q10 , which occurs in the human organism is ubiquinone referred. The term coenzyme Q, however, is the collective term for all common occurring ubiquinones.
Ubiquinone is found in most animal and plant foods. In the human body particularly large amounts in the heart, kidneys and liver are present.
Coenzyme Q10 plays an important role in energy production. It acts in the so-called respiratory chain as an electron carrier. In addition, it may have importance in the degradation of free radicals, thereby reducing oxidative stress and prevents its sequelae. It can recover spent vitamin E, so that it may use as an antioxidant of the body again.
With the food we take daily something three to ten milligrams of coenzyme Q10 to us. It is neither a vitamin nor the body is dependent on that he gets it about the diet because he can synthesize in sufficient quantity itself.
The Q10 content in the body decreases with age. Therefore Q10 is sometimes used preventively in seniors.
Physical exertion, stress, alcohol and nicotine consumption and diseases can increase the demand, so that under certain circumstances, supplementation with nutritional supplements can be taken into account.
A deficiency of coenzyme Q10 was, however, not been demonstrated in humans.
For a preventive intake , for example anti-aging, protect against heart attack, heart diseases, with heart failure, muscle weakness, tumors, etc. missing until now the scientific basis. Nevertheless, it is used abroad to accompany therapy in heart failure. The intake of coenzyme Q10 appears to have beneficial effects even when simvastatin-containing medicinal therapy.
If you want to take coenzyme Q10
Then, as usual dose 30 to 120 mg per day. Anti-aging experts recommend for staying young from the age of 50, a total daily dose of 30-150 mg. By taking 60-100 mg of coenzyme Q10 per day already the mirror doubled in the blood.
At best the body can absorb the Q10 from gelatin capsules that are taken several times a day with meals.
These foods contain a great deal ...
Coenzyme Q10 is found in many foods, but only in small quantities. Particularly rich in Q10 are:
Meat in general
Wheat germ, whole grain bran
Broccoli, soybeans, green beans, spinach, cabbage, garlic
Fruit / nuts
Walnut oil, almond oil