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Royal Jelly: Benefits, Side Effects, Uses, Dosage, Warnings?

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ROYAL JELLY: Benefits, Side Effects, Uses, Dosage, Warnings?

Other name: milk bees.

Indications
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Traditional use
Reduce physical and mental fatigue and stress, enhance immunity, support convalescent treat sexual and menstrual disorders.
See legend of symbols
For details, see Research on royal jelly .

Dose of royal jelly
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Fatigue, stress, convalescence

Take 100 mg to 250 mg daily of royal jelly lyophilized or 300 mg to 750 mg of fresh royal jelly. Traditionally, it is recommended to take royal jelly before breakfast, for 4 to 6 weeks. Some authors suggest to consume up to 1.2 grams per day of fresh frozen (400 mg jelly freeze) at the beginning of a treatment for fatigue.
Attention. Due to the allergenic potential of royal jelly, it is best to start with a low dose and increase gradually.

Description of royal jelly
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The royal jelly is whitish, gelatinous substance secreted by certain glands of young bees feeder. It is intended to feed the larvae in the first stage of development and is the exclusive diet of queens throughout their existence. Also called "milk bees", it contains from 50% to 65% water and many other substances, including:
- sugar (15%), mainly fructose and glucose;
- proteins (18% 13%),
- the fat (3% to 6%)
- minerals (1.5%),
- vitamins, particularly those of the B group, including B1 and B5;
- trace elements (inorganic in trace amounts).

Attributed in part to the royal jelly that the queen, who is nourished exclusively, much larger than the other bees, and live 5 or 6 years, while the active life of the workers barely exceeds 45 days. Some manufacturers and distributors take the opportunity to extol the supposedly miraculous effects of their products, a dubious extrapolation. Indeed, other insects grow very quickly without royal jelly and longevity of insects are not the same mechanisms as the human one . For details, see the section on the shelves .

Normally, the amount of royal jelly produced in a hive is barely enough to support growth of larvae and feeding the queen. To obtain the desired quantities, beekeepers remove the queen of the hive. They thus encourage workers to raise several larvae destined to produce queens and therefore produce more royal jelly. Before these techniques are developed, royal jelly remained a scarce commodity and relatively unknown.

History of royal jelly
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It is said that the rulers of ancient Chinese royal jelly attributed the power to ensure the longevity and sexual vigor . This is however only 70 years to 80 years that it has become really popular with the Chinese. It is present in many preparations for the treatment of arthritic pain, hypertension, diabetes, chronic hepatitis, menstrual disorders, infertility and fatigue. In Chinese medicine , this substance is considered a tonic for deficiency of Yin .

There is a similar tradition popular in Eastern Europe and Russia, where the royal jelly is considered an adaptogen. An adaptogen is a substance that increases in general and non-specific resistance of the organism to various stresses that reach. While causing minimal side effects, adaptogens exert nonspecific normalizing action on many organs and physiological functions.

At the beginning of XX th century, beekeepers have developed techniques for the production of royal jelly on an industrial scale. The industrial production and use of lyophilization (freeze-drying process) helped popularize royal jelly throughout the world. In Japan, for example, consumes in genki , especially popular tonic beverages to office workers. China is the world's largest producer of royal jelly.

Research on royal jelly
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Very few rigorous scientific studies on the therapeutic effect of royal jelly in humans have been published. It has especially tests in vitro and in animals. The product, however, has long been used in traditional ways to reduce the physical and mental fatigue and stress, enhance immunity, support convalescents and treat sexual and menstrual disorders.

Traditional use Menopause. According to data in vitro and in animals, the royal jelly contains compounds with estrogenic activity 2-5 , which may partly explain its traditional use for menstrual disorders in women. Two Japanese clinical trials from the 1970s suggest that royal jelly can have a positive effect on the hormonal balance in postmenopausal women, but there is no detail to assess their methodological quality 6-7 .

Two more recent preliminary clinical studies, including one without placebo, on a preparation containing royal jelly, pollen and vitamin C (Melbrosia®) gave good results in the reduction of many symptoms of menopause 8 9 . However, as it is a product containing other ingredients, it is unclear what role the royal jelly has played in these studies.

Traditional use Immunity. A number of animal studies and in vitro and found to have immune immunomodulatory activity of royal jelly 13.17 . These actions are common substances adaptogenic and have been granted to certain fatty acids and proteins that royal jelly contains.

Various
Although the treatment of hyperlipidemia is not part of the traditional indications of royal jelly , some researchers have studied this indication. Current evidence is not convincing. A series of studies conducted in Europe in the 1960s have shown positive results, but their methodological quality leaves much to be desired 10 . Two recent trials have yielded interesting results on cholesterol, but their methodology is also low (no placebo group, in particular) 11.12 .

Royal jelly is used to combat allergies . However, in a study involving 64 children, treatment, taken 3 to 6 months before the pollen season, was not more effective than placebo for changing the incidence and severity of allergic rhinitis (hay fever) 14 .

An ointment made ​​from royal jelly and vitamin B5 (Pedyhar®), in addition to other routine interventions, promoted wound healing 60 diabetic patients with serious foot ulcers 15 .

In a preliminary trial in humans, a single dose of royal jelly has reduced the amount of sugar in the blood of healthy subjects 16 .

Several researchers, mainly in Japan, explore the effects of royal jelly on animals 17 . Some examples: protection against toxicity of ciplastine (an anticancer drug) 18.19 ; protective effect on cognitive function in mice exposed to a neurotoxin 20 ; acceleration of healing of oral inflammation (mucositis) 21 ; Anti-fatigue effect 22 and hypotensive 23.24 ; stimulatory effect on the thyroid gland 25 ; treatment of colitis 26 .

Precautions
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Watch out
Some authors claim that one can safely take up to 1.2 g of royal jelly per day and even 27 . However, it is important to start with a low dosage and gradually increase it to detect possible allergy.
In the years 2000 to 2009 were detected cases of contamination chloramphenicol (antibiotic toxic in high doses) in Italy, the UK and Australia, particularly in products imported from China 28-31 . In general, the detected amounts are minimal, but the use of chloramphenicol is banned in animal husbandry in the mentioned countries as well as Canada. His presence is not permitted, nor in imported products.
Cons-indications
The people who are allergic to honey, pollen, bee stings and plants of the composite family (daisy, echinacea, dandelion, etc.) could also be in the royal jelly.
There have been several allergic reactions and anaphylactic royal jelly 32-36 , including in subjects with asthma or atopic eczema.
Adverse effects
Topical use, royal jelly can cause or exacerbate dermatitis ( inflammation of the skin).
Interactions
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With plants or supplements
None known.
With drugs
Was assigned to the royal jelly a loss of blood in the urine (hematuria) in an elderly patient with non-Hodgkin lymphoma and hypertension and taking warfarin, an anticoagulant 37 . However, the link between cause and effect has not been clearly established.
In mice, consumption of royal jelly (5% of the diet) had no impact on liver enzymes of drug metabolism 38 .
On the shelves
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The royal jelly must be kept fresh in the freezer, away from air, moisture and light. If it is lyophilized , these precautions are not necessary. Such as royal jelly loses during lyophilization about two-thirds of its weight, 100 mg of lyophilized jelly correspond to 300 mg of fresh frozen.

In addition to the fresh royal jelly (sold in a jar) and lyophilized (presented in capsules) there are commercially preparations of honey and royal jelly. There are also liquid, usually presented in ampoules, and which contain, in addition to royal jelly, honey, pollen, propolis or ginseng in varying proportions.

Some products on the market have a standardized content of 10-2 HDA (10-hydroxy-2 decenoic), a lipid active ingredients of royal jelly which also serves as a marker.

Since the late 1990s, the Food and Drug Administration regularly called to order manufacturers and distributors of royal jelly . Indeed, many of them are unfounded allegations about the virtues of their product: cure arthritis, kidney disease and fractures, antibiotic effect, weight loss, to name a few 39-41 .

Royal jelly is one of the richest one can find in nature substances. Royal Jelly is powerful body and head with soothing regenerating. It is also an excellent natural anti-wrinkle skin. The extraordinary natural virtues of royal jelly require utmost precision in production.

Our Royal Jelly here.

Royal jelly organic French, potting at harvest pure and freshRoyal Jelly, a magical and precious milk
Royal jelly is like a milk. Its quality depends on the conditions of life and feeding bees. Just as the stress of the mother can affect the quality of her milk, it is important that the bees are not stressed or abused: bees "forced" fed sugar syrup or cereal by-products could not produce a "milk" as rich. , we can say with pride that our royal jelly is one of the best in the world. For us it is a substance "premium" rare and precious. We put it in a pot in hand within a few hours of harvest.

Why is our royal jelly richer and more active?
Our Royal Jelly is certified organic and 100% French
Beekeeping DOUCE® Our method ensures organic royal jelly, fresh and of high quality. She was born in France with optimal wealth of active ingredients, a living structure and excellent vibrational field (Exclusive patent Ballot-Flurin No. FR06 51412).
Love bees and harvesting method Beekeeping DOUCE®
We maintain a rigorous homemade (no queen rearing and no artificial food). Our bees forage only flowers from forage areas preserved rich and secular. Royal Jelly is harvested in the Southwest during honey flow at a rate of only a few grams per hive, from May to August.
Great naturalness
Our organic and fresh royal jelly is presented in its original state, as secreted by bees, manually filtered with a simple nylon fabric end and potting in hand within hours of harvest. It is naturally kept cool since its harvest, and we guarantee it is neither spun nor frozen, and neither dehydrated.
Revitalization and deep respect for the rhythms of nature
At harvest time, we ensure a positive mindset for the beekeeper and adapt to secular rhythm bees never forcing a crop. We respect the solar, lunar and planetary calendars.
Exclusive formulations: the art of observing nature.
preparations we use our many local varieties of royal jelly for use or Apicosmétique® Health & Wellness adapted (royal jelly senior camps Belmont, Balas of the forests, slopes of the Pouchette ...). Our Honey cure® "Honey and royal jelly" contains a precise dose of royal jelly, modeled on the mix are themselves the nurses from the hive for future bees. Preparation is driven by a slow manual mixing in honey for maximum absorption by the body, and good storage at room temperature.
The remarkable properties of royal jelly
Royal Jelly is a "royal" ingredient secreted by the nurse bees to feed their queen, which then has a long life and exceptional fertility. Royal Jelly is one of the richest one can find in nature substances. It contains valuable vitamins essential for the metabolism of every cell, and a multitude of minerals (calcium, iron, potassium ...), amino acids, sex hormones ... The list goes on! Some of the active substances contained in Royal Jelly:

Active ingredients and remarkable properties of royal jelly
Proteins,
nucleic acids (DNA, RNA), amino acids (including the 8 essential amino acids) Construction and reconstruction of the body
Carbohydrates
glucose and fructose mainly Energy
10-HDA acid
and fatty acids Anti-bacterial, anti-fungal and anti-germ (Proteus, Escherichia coli, Streptococcus, Staphilococus aureus, Mycobacterium tuberculosis), may be anti-tumor
Concentrated vitamin
B group especially including pantothenic acid or vitamin B5 Save the oxygenation of cells, activation of metabolic processes, retarding aging (skin, hair, nails)
Natural acetylcholine Tonic stimulates adrenaline, nervous system (mediator of the transmission of nerve impulses at the synaptic level), vasodilator
Gammaglobuline Stimulates the immune system
Royalisin
proteinaceous substance Antibacterial and antibiotic
Neopterin Helps to fight against infectious diseases
Gelatin Softens the skin, helps heal bones and skin (the precursor of collagen)
Active water
Information and cohesion of lifeRoyal Jelly BIO AB, Origin: France

Origins of Royal Jelly
When a hive has more than 60,000 bees, one queen no longer sufficient to ensure the cohesion of the colony. Then the bees get in duty to raise a new queen. The new queen will experience a growth of express 13 days. The old queen will leave with a swarm of bees living in a new place: your fireplace, an empty hive or the trunk of a hollow tree. How are they working to elect and raise a new queen? These are the nurses, young old bees from five to fifteen days, which begin to secrete a "magic milk" from special glands in their jaws and back of their head. This milk is strictly subject to the queen. Only the very young larvae of worker bees have the right to enjoy it during the first three days of life, then they are fed pollen and honey. Thanks to this "magic milk" named royal jelly, the queen will grow two times faster than a worker, her ovaries will be fully developed and, importantly, it will live five years while a simple working lives only a few weeks. This ingredient "royal" secreted by nurse bees allows the queen live 40 times longer than the worker . This substance gives itself the difference between the queen mother of the hive, very active, laying tireless and workers, female inactive ovaries.

The benefits of Royal Jelly
The three main areas of application of Royal Jelly:

Health, fitness and vitality of the body
Royal jelly involved in the overall vitality of the body, regardless of age (resistance to cold, physical strength). It promotes tissue oxygenation and is beneficial for sexuality, especially of women, and for menopausal disorders. Its antiviral properties help fight against influenza and herpes. Suitable for active people, convalescents, elderly, children and athletes, it is also suitable for pregnant women during pregnancy, and young mothers overwhelmed.

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