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Chitosan: Benefits, Side Effects, Uses, Dosage, Warnings?

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CHITOSAN: Benefits, Side Effects, Uses, Dosage, Warnings?

Chitosan is a fat binding slimming pill, which is used to support the treatment of obesity, weight control and as a lipid-lowering agent. Chitosan is not approved as a drug and is sold as a medical device or nutritional supplement. Possible adverse effects include indigestion and allergic reactions. The clinical effectiveness is not scientifically proven, in our view.
synonym: chitosan INCI , polyglucosamine , Poliglusam , Deacetylchitin , chitosan hydrochloride Ph Eur , Kitosan

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Products

Chitosan is in Switzerland in the form of tablets and capsules (eg Formoline L112®, Reduzell 36®). It is not a drug, but as a medical product or food supplement in the trade. The various products differ in the dosage form, the dosage in the excipients used, the molecular weight, the degree of deacetylation and the fat binding capacity. Chitosan is also used as a pharmaceutical excipient, for wound dressings and numerous other purposes. This article refers to the taking against obesity .

Structure and Properties

Chitosan is a β-1.4-polymer selected from linear, unbranched chains of D-glucosamine and N -acetyl-D-glucosamine is. It is therefore also referred to as polyglucosamine. Chitosan is obtained by alkaline deacetylation of chitin, a polymer of N -acetyl-D-glucosamine, which is extracted from the shells of shrimp and crabs. It is a modified natural product. The various chitosans differ in the degree of deacetylation. Figure 1 shows a section of a chain. The amino group can be protonated and thus positively charged.

Effects

Chitosan to bind lipids contained in food and thus inhibit its absorption by being enclosed in a gel excreted in the feces. Chitosan to lipid lowering be lower LDL and raise HDL. It is positively charged, and will bind to negatively charged fatty acids. It also swells with water, can act as light filling and shorten the intestinal transit time.

The clinical efficacy in the claimed applications is controversial and scientifically insufficient evidence, in our view. Although it has been the ability to bind lipids, and demonstrating in vitro. The systematic analysis of the performed scientific studies showing little effect with respect to body weight and cholesterol, but the poor quality of many studies does not allow a definite conclusion to be. From the makers independently conducted studies of good quality point to a lack of efficacy (eg, Jull et al., 2008).

Areas of application

Chitosan is a fat binder to support the treatment of obesity , weight control and as lipid-lowering drugs to reduce cholesterol and LDL used.

Dosage

Chitosan is usually taken twice a day to fatty meals with sufficient water. Since it is a dietary fiber, should be drunk enough (approximately 2 to 3 L) during the day. It should not be taken dissolved in water. It is recommended that chitosan only to take two of three main meals, so that the organism is a sufficient supply of fat-soluble vitamins.

Contraindications

Chitosan should not be used in hypersensitivity, at a shellfish allergy in underweight in children under 3 years and not during pregnancy and lactation. In children and adolescents in the growth in the elderly, chronic digestive problems (constipation, bowel obstruction after a bowel operation, gastroparesis, intestinal polyps), inflammatory bowel disease, metabolic disorders or long-term drug intake chitosan should be used with caution.

Interactions

Since chitosan binds lipids, it may inhibit the absorption of fat-soluble drugs. These include, for example, oral contraceptives , hormones , retinoids and steroids. It is recommended that such drugs taking a temporal interval of 4 hours. Chitosan can also provide valuable food components such as fat-soluble vitamins and essential fatty acids bind. It should therefore only be taken a maximum of two of the three main meals (see above). Vitamins can also be supplied if necessary with a vitamin preparation.

Adverse effects

Possible adverse effects include both digestive complaints such as constipation , bloating , abdominal pain, diarrhea and bloating , on the other hand, allergic reactions such as skin rash, hives and itching . Chitosan exerts its effects locally in the intestine, is not digested and is not absorbed in the bloodstream.

chier infinity is the selection of agents which supposedly help you lose weight - and thus usually promise far more than they can deliver. One of the best selling "alternative" Gewichtsverminderern is currently chitosan. The substance is, simplistically stated, from pulverized shells of crabs and similar marine animals.

Adapted from ...
Healthy Living Issue 02/2010
These water-insoluble fibers, which can not absorb bowel bind fat; at least it can be shown in the test tube so that. What could be better than to believe in the human intestine passing similar? If fat would be bound in this way and excreted undigested, then the body would be deprived calorie nutrients. An effect that could be of course very well used for losing weight.

Assumptions are good evidence is better. The majority of studies show that the eliminated with the stool amount of fat does not increase significantly when taking chitosan. But the results are not uniform, and perhaps these laboratory data are not entirely reliable. As is so often true in medicine: What matters is what clinical studies suggest.

Here it is natural to restrict themselves to investigations with agents that do not contain potentially further weight-reducing substances other than chitosan. Furthermore, the studies should have a sufficiently long duration to actually show an effect can. Currently, there are seven studies that meet this requirement. Most of them show no effect of chitosan on body weight. Neither the duration of therapy nor the dose appear to exert a decisive influence. A meta-analysis of all placebo-controlled studies chitosan concludes that a reduction in weight can not be proven.

Potentially dangerous side effects
What works in the test tube works in the human gut apparently not as hoped. So bad cards for the currently popular for Slimming. If we illuminate the question of whether chitosan can potentially cause harm, the sheet looks even worse. Because if the fiber in the intestine should bind small amounts of fat but, as he does in the test tube, then there is a danger that through this mechanism the body are deprived of vital substances, such as fat-soluble vitamins or medications. In fact, there are some indications that this could be a potentially serious side effect of chitosan. Finally, we should also consider the impact on your wallet mention: chitosan supplements are not cheap.

Bottom line is for chitosan So out very little. Scientific studies speak against efficacy, the side effects are potentially dangerous. For me, it allows only one conclusion: Hands off!

Lose weight with chitosan
Just swallow a few capsules and you will tumble the pounds. Sounds too good and easy to be true. Suppliers of fat blockers such as chitosan, a purely natural substance that promise great customer order. But how promising the powders and capsules with the alleged miracle cure really? Find out here if you can achieve your dream figure with chitosan or better leave it alone should. Our complete diet test illuminates the miracle pills from all sides and reveals how they really are recommended.

The chitosan substance is awarded by followers an almost miraculous effect. Does losing weight with the natural miracle cure really? We have tested it.
The chitosan substance is awarded by followers an almost miraculous effect. Does losing weight with the natural miracle cure really? We have tested it.
photocase.com © clausiaarndt
Survey
Chitosan is one of the most used ingredients for fat blocker. The natural substance is extracted from the shells of marine animals, but also from fungi and yeast. The chitosan substance is awarded by followers an almost miraculous effect. But is it really reasonable to praise chitosan as a healthy miracle drug that helps or is caused only a placebo effect at the end you lose weight?

We Lose weight with chitosan considered a closer and examined for the implementation, the implementation in daily life, the science, the integration of movement and sport as well as the long-term effect.

Procedure
implementation in everyday
scientific
Fitness & Sport
Long-term effect
Overall rating
of Nadja Greiner
(2.5 out of 5 stars)
Method
Reviewed by Nadja Greiner
(4 out of 5 stars)
Chitosan fat blockers are available in powder and capsule form. Depending on the package insert, take the capsules or powder (for example, 6 capsules per day). Many representatives claim that you can indulge as much as you want. But few also recommend a calorie and low-fat diet. Too, we recommend a balanced diet.

Implementation in daily life
Reviewed by Nadja Greiner
(3 out of 5 stars)
A pack of 90 capsules costs 8-20 euros depending on the provider - for every budget so there is something. Referring now about 6 capsules per day, so one pack will last no less than two weeks. The intake also affected in any way everyday use because they are not limited by certain rules in food intake.

Wissensschaftlichkeit
Reviewed by Nadja Greiner
(2 out of 5 stars)
Representatives of chitosan products say the substances after a healing effect. So they cast down among other cholesterol levels, prevent high blood pressure, and kidney disease and curb obesity. Chitosan is a tough colorless natural substance which fat can bind. Once the capsules swell, gel-like mass which binds dietary fat - it is said that about 2 grams of chitosan can bind 14 grams of fat. In addition to fat and fat-soluble substances, such as vitamins, and bile acids are absorbed and excreted undigested. Therein lies the risk of chitosan products: required vitamins and other substances are excreted and it comes to a vitamin and nutrient deficiency. Also, you should check for any side effects with other medications. Persons holding a fish - and have shellfish allergy should steer clear of it.

Integration of movement and sport
Reviewed by Nadja Greiner
(1 out of 5 stars)
Most of chitosan capsules have any recommendations for a healthy and balanced diet, also sporting Activities are given little to no attention. However, exercise and balanced diet is permanently keep the weight important to be healthy and lose weight.

Long-term effect
Reviewed by Nadja Greiner
(2 out of 5 stars)
An exact duration of intake is not known - most are recommended about 3 to 9 months. Some studies support the efficacy of chitosan. However, the desired weight does not last very long.

Our conclusion
Chitosan Fat Blocker can help you lose weight quickly and effectively. If care is taken to prevent a nutrient deficiency, so this should also be done easily. However, we advise you to consult a doctor and seek advice. But you should remember that you can not permanently maintain desired weight without diet and exercise.

Article Wiki Closed - CHITOSAN: Benefits, Side Effects, Uses, Dosage, Warnings?
asked Aug 13, 2014 by Lancomega Level (10,245 points)
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