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Saw Palmetto: Benefits, Side Effects, Uses, Dosage, Warnings?

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SAW PALMETTO: Benefits, Side Effects, Uses, Dosage, Warnings?

Saw palmetto grows among other things on the coasts of Florida, where they really stand out for their large fan-shaped leaves. In autumn, the dwarf palm dark red fruits that contain high fat seeds forms. For the natives of Florida, the Seminoles put the berries are an important food - although they taste very bitter. From the branches made the Seminoles braids, they also used the fruit as a herbal medicine. In Europe, saw palmetto has been known as a medicinal herb in the 20th century.

What is the saw palmetto and where occurs the medicinal plant?

Saw Palmetto (Serenoa repens, Sabal serrulata) is a bushy dwarf palm that grows up to four feet tall. It has fan-shaped leaves, which consist of 18 to 24 single sheets. These are cut sharply at the edge. The flowers are arranged in densely hairy, piston-like inflorescences. The fruits and olives similar stain dark red. There are single-seeded berries that turn black when dried. Saw Palmetto is one of the palm family (Arecaceae) and occurs in the southeastern United States. It thrives on sandy soils and preferably a mild climate.

Which parts of plants and ingredients are used?

As a remedy, the fruits are used. They contain plant hormones - the so-called sterols. In particular, the substance beta-sitosterol plays a role among them. In addition there are long-chain sugar molecules, flavonoids and vegetable oil.

What do the ingredients? Whereas saw palmetto helps?

From laboratory experiments it is known that phytosterols have a hormone similar. Presumably attacks the substance beta-sitosterol in male hormone levels and slows the formation of dihydrotestosterone. This hormone is produced in the body from testosterone and probably (benign plays in the development of benign prostate enlargement prostate ) play a role.

There are several herbal remedies that either only Sägepalmenfrüchte or various combinations of saw palmetto, pumpkin and nettle contain. They should help men to whom the prostate causes problems and who have urinary symptoms among others. Studies, there are now many, but they come to different results. It probably depends on what herbs combinations occur in the preparations, such as high doses they are and what processes the contents were extracted from the plant.

Whether Sägepalmenfrüchte actually beneficial to the prostate may affect, is not yet finally resolved. How useful is the ingestion, patients should discuss with their best urologist.

Important: If you frequently have to go to the bathroom, his bladder can not empty completely or at night feels constant urge to urinate, the symptoms definitely should be to clarify the physician.

Important notes:

Sägepalmenfrüchte call rarely produce side effects. Sometimes it can cause gastrointestinal discomfort.

How effective are selected medication from the pharmacy? Is there convincing data on the efficacy of herbal medicines? When to natural remedies work? As it is with the effects of vitamins and minerals? The following contributions Rate medicines and natural remedies on the basis of current scientific publications.

Sägepalmenfrüchte extract (Serenoa repens) in the treatment of benign prostate enlargement - effective or ineffective?

Sägepalmenfrüchte extract for the treatment of benign prostate enlargement

Background
From the fruits of saw palmetto (Serenoa repens), a native to the southeastern United States palm, agents for the treatment of benign prostatic hyperplasia be won.

Benign prostatic syndrome (BPS) and benign prostatic hyperplasia (BPH) designate the same disease. This is called a benign enlargement of the prostate (prostate). To BPH, it usually comes in men in the mid to later life. At about 25 to 30 percent of all men with an enlarged prostate symptoms occur. These include nocturnal urination, urinary retention or an attenuated urine.

In Germany there are several medicines that Sägepalmenfrüchte extract (Saw palmetto berry extract) containing as an active ingredient: eg Serenoa-ratiopharm, Talso Uno N, Sabal Stada uno, Prosta-Urgenin Uno and others. The approved indications are urinary symptoms in benign enlargement of the prostate (micturition problems with BPH stage I to II according to Alken or II to III according Vahlensieck).

Neither the American nor the German guidelines of urological societies recommend the use of phytotherapeutic agents (eg saw palmetto, nettle, pumpkin) for the treatment of benign prostatic syndrome (4).

Studies on the effectiveness of Sägepalmenfrüchte extracts
To evaluate the effectiveness of Sägepalmenfrüchte extracts (Serenoa repens) in the treatment of benign prostatic syndrome (benign prostatic hyperplasia, BPH) are two Cochrane meta-analyzes before (1, 11). In the first analysis from the year 2009, the data of 5222 patients from 30 randomized trials were considered.

The result was clear: Serenoa repens was not superior to placebo in terms of the internationally recognized IPSS symptom score. When symptom "nocturnal urination" no difference could be documented with placebo in studies. Even when individual functional parameters, such as the urinary peak flow, the Sägepalmenfrüchte extract showed no better effect than a placebo. To assess the long-term effect of the change in size of the prostate was measured by ultrasound in the studies. Also in this parameter Serenoa repens was not more effective than placebo.

Conclusions: The authors of this meta-analysis came to the conclusion that Sägepalmenfrüchte extract for the treatment of symptoms that are caused by a benign prostate enlargement, was no more effective than placebo (1) .

Further studies on the effectiveness of Sägepalmenfrüchte extracts
In 2007 came a comprehensive analysis, published in the journal drug regulation in practice (8), similar results. The previously known findings were supplemented in particular by the following study.

Sägepalmenfrüchte extract in prostate hyperplasia?
In a high-quality work (prospective, double-blind, randomized, placebo-controlled), the effect was of Sägepalmenfrüchte extract (160 mg 2 times daily) in 225 men> 49 years) examined (7). The study ran for over a year. The indications were moderate to severe BPH symptoms (Auasi score = American Urological Association symptom index of at least 8 points and a maximum urinary flow rate of less than 15 ml / sec.). Endpoints of the study were: Auasi score, maximum urinary flow rate, prostate size, residual urine volume, quality of life, laboratory values ​​and compatibility. Results: After one year, no differences between active treatments and placebo were detectable. Strictly speaking, the results apply only to those used in the study Sägepalmenfrüchte extract, but fully complied with the requirements of U.S. Pharmacopoeia for Sägepalmenfrüchte- extract. Conclusion: The treatment with 320 mg Sägepalmenfrüchte extract daily for one year, the symptoms were caused by a benign enlargement of the prostate, not improved compared to placebo.

Update on the effectiveness 2012
In a recent Cochrane meta-analysis on the efficacy of Sägepalmenfrüchte extracts (9) Another study data could not be included, but the assessment described above for the effectiveness of Sägepalmenfrüchte extracts did not change.

A long-term study (72 weeks) found itself under the double and three times the standard dose no difference in disease-specific symptom score (Auasi) compared with placebo (10). In another high-quality study, the Serenoa repens-therapy long term in improving nocturia (urination at night) was not more effective than placebo. The few study results that repens document a positive influence of Serenoa on the symptoms of prostatic hyperplasia (12, 13), all without a placebo control carried out, which significantly limits their meaningfulness.
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Compatibility
The tolerability of Serenoa repens extracts-is evaluated in the literature, with few exceptions as well. Adverse events were rare and mild with Serenoa repens-extracts and their incidence was not statistically significantly different from placebo. There are isolated case reports of pancreatitis (2) and coagulation disorders (3) before. On interactions with other medicines has not been reported.

Conclusion
The previous study data summary, Sägepalmenfrüchte extracts in the treatment of symptoms of benign enlargement of the prostate are not effective.

Article Wiki Closed - SAW PALMETTO: Benefits, Side Effects, Uses, Dosage, Warnings?
asked Aug 13, 2014 by Lancomega Level (10,245 points)
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