St. John's Wort: Benefits, Side Effects, Uses, Dosage, Warnings?


ST. JOHN'S WORT: Benefits, Side Effects, Uses, Dosage, Warnings?

Pregnancy, Anxiety, Benefits, Contraception, Depression, Dosage
Effects, Pregnant Woman, Fatigue, Oil, Interactions, Drugs, Dosage.

St. John's Wort St. John's wort: Definition

The wort is an herb. Its flowers and leaves are used in medicine .

The wort is most commonly used to treat cases of depression and conditions that sometimes go with depression such as the anxiety , the tiredness , a loss of appetite and sleep disorders . There is strong scientific evidence showing its effectiveness for mild depression to moderate .

Other uses of St. John's wort include heart palpitations , the mood swings and other menopausal symptoms , an attention deficit with hyperactivity disorder , the obsessive-compulsive disorder (OCD) and seasonal affective disorder .

The St. John's wort has been found to be effective against the exhaustion , to help stop smoking , against the fibromyalgia , the chronic fatigue syndrome , the migraine and other types of headaches , muscle pain , nerve pain and bowel syndrome irritable .

St. John's wort: Use and Operation

An oil can be made ​​from the wort . Some people apply this oil on the skin to treat bruises and abrasions , the inflammation and muscle pain , the burning of the first degree, the wounds , the insect bites , the hemorrhoids and nerve pain . But the application of the wort directly to the skin is risky. It can cause severe sun sensitivity .

The wort is native to Europe. We commonly found in dry soil along roadsides, meadows and woods.

France banned the use of products derived from wort . The ban appears to be based on the important interactions between St. John's wort and certain medications .

St. John's wort: Effectiveness

Despite its high profile, the St. John's wort does not have all the virtues that we are willing to lend. The St. John's wort may even be dangerous thinking process, wrongly certain serious conditions. As follows:

The wort is probably effective for:

Treat a mild to moderate depression : Taking extracts wort improves mood and reduces the anxiety and insomnia associated with depression . It seems about as effective for treating depression that many drugs.
The St. John's wort may be effective for:

The symptoms of menopause : Some research shows that the combination of St. John's wort with black cohosh can help improve the symptoms of menopause
The somatization : Treatment with St. John's wort appears to reduce symptoms after 6 weeks of treatment.
The wound healing
The wort is probably ineffective for:

The Attention Deficit Hyperactivity Disorder : Take extract of St. John's wort does not appear to improve symptoms in children aged 6-17 years
The hepatitis C
The irritable bowel syndrome
The pain associated with diabetes (neuropathy)

There is insufficient evidence of effectiveness rate of wort for:

The obsessive-compulsive disorder (OCD) : There is evidence contradict ory as to the effectiveness of St. John's wort for OCD .
The premenstrual syndrome : Preliminary data indicate that St. John's wort may help reduce the symptoms of premenstrual syndrome.
The Seasonal Affective Disorder : Early studies suggest that St. John's wort may help overcome seasonal affective disorder. Apparently improve symptoms of anxiety , decrease libido and sleep disturbances associated with seasonal depression.
The cessation
The stomach
The bruising
The skin conditions
The migraines
The neuropathic pain
The sciatic
The fibromyalgia
The chronic fatigue syndrome
The muscle pain
The cancer
The weight loss
St. John's wort: Actions

For many years, researchers thought that a chemical present in the wort called hypericin was responsible for its effects against the depression . More recent reports suggest that another chemical, the hyperforin , may play a greater role in depression .

St. John's wort: Risks

The wort is a priori safe for most people when taken orally and short term.

St. John's wort: Side Effects

The St. John's wort can cause side effects such as trouble sleeping , vivid dreams of, the agitation , the anxiety , the irritability , the stomach pain , the tiredness , a dry mouth , the dizziness , the headaches , the rashes , the diarrhea and tingling .

Take St. John's Wort in the morning or decrease in the dose if it appears to be the cause of sleep problems .

The St. John's wort appears to be safe when taken in children under 12 for up to 6 weeks.

However, St. John's wort is likely unsafe when taken orally at high doses. It can cause severe reactions to sun exposure .

St. John's wort: Special precautions and warnings

St. John's wort: Pregnancy and lactation

The wort is likely unsafe when taken during pregnancy . There is some evidence that it can cause birth defects in rats. Nobody knows yet if the wort has the same effect on humans. Until we know a little more, do not use St. John's wort if you are pregnant or breastfeeding.

St. John's wort: Infertility

There are risks associated with taking St. John's wort on the success in the design of a child. So if you try to have a child, do not take St. John's wort , especially if you have experienced problems with fertility .

St. John's wort: Attention Deficit Hyperactivity Disorder (ADHD)

There is some doubt in the fact that St. John's wort may exacerbate symptoms of ADHD, particularly in people taking medicines containing methylphenidate . Until we know a little more, do not take St. John's wort if you are taking methylphenidate. In any case, consult your doctor.

St. John's wort: Bipolar Disorder

People with bipolar disorder are in a state situated between depression and mania , a condition marked by excessive physical activity and impulsive behavior . The St. John's wort can affect the mania in these individuals and may also accelerate the cycle between depression and mania .

Sluice thousand: Major Depression

In people suffering from major depression , the wort may act on mania, a condition marked by excessive physical activity and impulsive behavior.

St. John's wort: Schizophrenia

The St. John's wort may act on psychosis in some people with schizophrenia .

St. John's wort: Alzheimer's disease

It is feared that the wort might contribute to dementia in people with Alzheimer's disease .

St. John's wort: anesthesia and surgery

The use of anesthesia in people who used St. John's Wort could lead to serious heart complications during surgery . Stop using the wort at least two weeks before a scheduled surgery and talk to your doctor, surgeon and anesthetist.

St. John's wort: Interactions with herbs and supplements

There are no known interactions of St John's wort with herbs and supplements.

St. John's wort: Interactions with foods

There are no known interactions of St John's wort with food.

St. John's wort: Determination

Please note, doses below are by no means a prescription but only a statement assays wort usually offered. Never take St. John's wort without medical advice.

For mild depression to moderate:
When using the wort extract standardized to 0.3% hypericin content 300 mg three times daily.
When using wort extract is standardized to 0.2% hypericin: 250 mg twice daily.
When using wort extract is standardized to 5% hyperforin: 300 mg three times daily.
For children under age 12 suffering from depression: St. John's wort extract standardized to 0.3% hypericin 300 mg daily.
For premenstrual syndrome (PMS) : St. John's wort extract standardized to 0.3% hypericin dosed at 300 mg once daily.
For the symptoms associated with depression of the body : 300 mg three times a day of the extract standardized hypericin was used.
For somatization : a specific extract of 600 mg / day was used.
Do not suddenly stop taking St. John's wort . This can cause side effects unpleasant. If you decide to stop taking St. John's wort , reduce the dose slowly over time.

The information on this site does not necessarily reflect the author and are provided for information only. Also, consult a health care professional with any questions regarding the wort .

St. John's wort: Forum and Testimonials

Your experience on the St. John's wort may be of interest to others. Think about it!

We invite you to leave your comments in the forum below.


St. John's Wort is a perennial plant whose flowers with five yellow petals appear in early summer. It is also called the herb St. John. In the Middle Ages St. John's Wort is starting to be known for treating neurological disorders ( anxiety , irritability or migraine ). In Germany, since 1988, St. John's wort is officially recognized as a drug antidepressant . It is today, in this country, the first drug prescribed if depression mild to moderate (seasonal affective disorder, depression or reactive depression is not related to another disease).
Active molecules

The effects antidepressant St. John's wort has long been attributed to hypericin. Indeed, it was shown that hypericin has the ability to inhibit MAO inhibitors (a monoamine oxidase ). However, in recent years, the mechanisms of antidepressant St. John's wort were revalued on more complex models: the whole plant extracts are currently more efficient than any particular individual component.

If the tests are examined in vitro , in animals or humans, antidepressives virtues of St. John's wort are not in doubt. Several studies in placebo double blind even compare the wort to some synthetic antidepressants
Therapeutic spectrum of wort may also extend to the treatment of smoking cessation and psychological problems related to menopause . In addition, St. John's wort appears to be extremely well tolerated and produce very minimal side effects (upset stomach in less than 1% of cases).

St. John's wort is available in many forms. It can be eaten in infusion (2 to 4 g of dried flowers three times daily), in the dyeing (3-6 ml three times a day), oil (a teaspoon three times a day). In capsules (standardized to 0.3% hypericin), the plant is available in various dosages ranging from 125 to 1000 mg. The normally recommended dose for the start of treatment is 300 mg three times daily. A treatment lasts minium six weeks, they were seen effects to 3-4 weeks.
Side Effects

St. John's wort is characterized by very few side effects (less than 6% of cases). Sometimes there is:
mild digestive disorders ,
a feeling of tiredness ,
of allergies skin,
increased irritability.


St. John's wort interacts with many substances. If you are undergoing treatment, it is imperative to consult your doctor. Among the reported interactions, we report the acitétrine the anesthetic , amsacrine, the anticoagulants , antidiabetics, beta-blockers , the buspirone , contraceptives, cyclosporine, digoxin , the étosopide the irinoticam the methadone , phenytoin, protease inhibitors, reserpine, statins, tamoxifen, theophylline, trazodone. Simultaneous use of St. John's wort and antidepressants (or anxiolytics ) synthesis is not recommended. Sources: Kasper S, Gastpar M, Müller WE, Volz HP, Dienel A, Kieser M, Möller HJ. (2008) Efficacy of St. John's wort extract WS 5570 in acute treatment of mild depression: a reanalysis of data from controlled clinical trials, Eur Arch Psychiatry Clin Neurosci.

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asked Aug 12, 2014 by Lancomega Level (10,245 points)